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Dr. John Grohol's weekly update of news and articles on psychology. Since 1999.

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Placebo Response Persists in Depression

Posted on August 05, 2008

There has been considerable debate ever since PLoS Medicine published a study in February suggesting that antidepressants are largely no better than a placebo (sugar pill) for the treatment of depression. The only condition where the researchers found a significant difference was in severe depression, and this was only because the placebo response dropped off not because the antidepressant medication s response increased. I commented on the study at the time suggesting that while adding to our understanding of antidepressant medications, it was hardly without faults. Other meta-analyse...

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Tags:
antidepressant , antidepressants , depression
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