In the Pipeline
In In the Pipeline - Posted 6 days ago
The pace of research has noticeably slowed today here in the US. Most industrial labs will be empty tomorrow, Friday, and through the weekend, and eve...
In In the Pipeline - Posted 1 week ago
Avandia (rosiglitazone) has been under suspicion for the last couple of years, after data appeared suggesting a higher rate of cardiovascular problems...
In In the Pipeline - Posted 1 week ago
Since I was talking about Nitromed on Friday, let me mention another attempt to combine two known drugs into a new therapy. Another Cambridge company ...
In In the Pipeline - Posted 1 week ago
A colleague e-mailed me last night with an observation that he d heard recently: Have you noticed, he said, that the number we use get less...
In In the Pipeline - Posted 1 week ago
I know that it s not necessarily fair to drag out old press releases, but let s do it anyway. Many readers will remember a few years back when Nov...
Tags: hearing
In In the Pipeline - Posted 2 weeks ago
One of the more wide-ranging on my Lowe s Laws of the Lab list is this: The secret of success in synthetic chemistry is knowing what you can a...
Tags: organic
In In the Pipeline - Posted 2 weeks ago
So, you re making an enzyme inhibitor drug, some compound that s going to go into the protein s active site and gum up the works. You usually wa...
In In the Pipeline - Posted 2 weeks ago
Organic chemisty can be a real high-wire act. If you re taking a compound along over a multistep sequence, everything has to work, at least to some ...
Tags: organic
In In the Pipeline - Posted 2 weeks ago
Should millions more people be taking Crestor? That s a real balancing act. You have a decrease in heart attacks, but from a fairly small incidence ...
In In the Pipeline - Posted 3 weeks ago
I wrote a while back about the problem of compounds sticking to labware. That sort of thing happens more often than you d think, and it can really h...
Subscribe to In the Pipeline