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Killing 'Angry' Immune Cells In Fat Could Fight Diabetes

Posted on October 07, 2008

October 7, 2008 (EurekAlert) - By killing off angry immune cells that take up residence in obese fat and muscle tissue, researchers have shown that they can rapidly reverse insulin resistance in obese mice. The findings reported in the October Cell Metabolism, a publication of Cell Press, suggest that treatments aimed at specific subsets of the so-called macrophage cells might offer a very effective new antidiabetic therapy, according to the researchers. We used a genetic 'trick' that allowed us to rapidly kill these macrophages, said Jerrold Olefsky of the University of California...

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diabetes , insulin , liver , obese , obesity , triglycerides , type 2 diabetes