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No Depression or Suicide Risk with Montelukast (Singulair) After All

Posted on September 03, 2008

In 2007, there were some concerns that suicide may be a complication of montelukast (Singulair) therapy.A retrospective study sponsored by the American Lung Association has found no evidence of depression or suicide linked to montelukast.The study findings will be published in an upcoming issue of the Journal of Allergy and Clinical Immunology.Leukotriene Receptor Antagonists (LTRA)Antagonists of the CysLT1 receptor (LTRA) are efficacious as controller therapy in asthma and montelukast is FDA-approved for treatment of seasonal allergic rhinitis.Mast cells quickly generate different mediators f...

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allergic , allergy , asthma , depression , essential fatty acids , fatty acids , lung , rhinitis