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Of Mice and Noise

Posted on August 27, 2008

BTBR mice are an inbred mouse strain that provide a mouse model of autism. BTBR mice are transgenic (their DNA contains an extra human gene thought to be involved in autism) and display social abnormalities and repetitive behaviors that correspond to the first and second diagnostic criteria for autism spectrum disorders. A recent study in PLOS One by Maria Luisa Scatton et al. investigates ultrasonic vocalizations in BTBR mice, in order to look at the second diagnostic criterion for ASDs, communication deficits. Scientists separately baby mice of different strains from their mother...

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autism , autistic , children , ear , infants