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Should food allergic children with history of anaphylaxis undergo challenge testing?

Posted on September 11, 2008

Should children with a history of anaphylaxis to foods undergo challenge testing?Background Data on the frequency of resolution of anaphylaxis to foods are not available, but such resolution is generally assumed to be rare. Results Eighteen of 21 children were sensitized to the food in question. Six DBPCFCs [double blind placebo controlled food challenge] were negative (29%): three for cows milk, one for egg, one for peanut, and one for wheat. In the positive DBPCFCs, no severe reactions occurred, and epinephrine administration was not required. Conclusions This is the first study using DB...

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allergic , allergy , anaphylaxis , children