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Heart muscle contraction shows newly discovered role of 2 enzymes

Posted on April 12, 2008

New research out of the University of Pittsburgh and the University of Chicago have discovered a new role for 2 enzymes and heart muscle contraction, histone acetyltransferases (HATs) and histone deacetylases (HDACs). Being in its early stages, it is none the less exciting in that it could provide new treatments As a possible treatment for such conditions as congestive heart failure, this technique could present an alternative to current therapies that counteract heart muscle weakness by boosting cellular calcium content, Shroff said. The heightened calcium improves muscle contraction but a...

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calcium , congestive heart failure , heart disease